U2's The Edge performs acoustic set at Sistine Chapel

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U2's The Edge became the first rock musician to perform at the Sistine Chapel this weekend when he played an acoustic set with a young Irish choir.

According to NBC News, The Edge (aka Dave Evans) was invited to take the stage in conjunction with the conference on regenerative medicine, which was held at the Vatican. The conference has a personal meaning for the guitarist, whose daughter had overcome leukemia.

"When I was asked to perform in the Sistine Chapel I didn't know what to say, because usually there's 'this other guy' who sings," he told the audience, making a joke about U2's Bono. "So it took me at least, well, 30 seconds to agree to it."

Evans performed U2's songs "Yahweh," "Ordinary World," and "Walk On," and Leonard Cohen's "If It Be Your Will."

See some fan-shot footage below.